Updated: Feb 24
“Cannabidiol (CBD) is a major phytocannabinoid present in the Cannabis sativa plant. It lacks the psychotomimetic and other psychotropic effects that the main plant compound Δ(9)-tetrahydrocannabinol (THC) being able, on the contrary, to antagonize these effects.-^v- It is now clear that CBD has therapeutic potential over a wide range of non-psychiatric and psychiatric disorders such as anxiety, depression and psychosis." Journal Citation (JC)-Campos AC, Moreira FA, Gomes FV, Del Bel EA, Guimarães FS. Multiple mechanisms involved in the large-spectrum therapeutic potential of cannabidiol in psychiatric disorders. Philos Trans R Soc Lond B Biol Sci. 2012;367(1607):3364-3378. doi:10.1098/rstb.2011.0389
. ”Following the initial report that it blocks the anxiogenic effects of high doses of the main psychoactive compound present in the Cannabis sativa plant, Δ9-tetrahydrocannabinol (THC)” (JC)-Zuardi A. W., Shirakawa I., Finkelfarb E., Karniol I. G. 1982. Action of cannabidiol on the anxiety and other effects produced by delta 9-THC in normal subjects. Psychopharmacology (Berl.) 76, 245–25010.1007/BF00432554 (doi:10.1007/BF00432554)
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